Enable MFA selectively when we create an application

I want to create an application for each of my tenants while using the rest API’s. How do I selectively enable MFA for some of the tenants using APIs?

The only API endpoint available for configuring an MFA policy is the policies endpoint, which allows you to make Org level MFA policies (will apply to all user or users in a specific group).

At this time, there is no public API available with which you can configure application specific MFA policies (like those found on an Applications Sign On tab)